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KMID : 0613820090190070928
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Journal of Life Science
2009 Volume.19 No. 7 p.928 ~ p.933
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Screening of Antiviral Activity from Natural Plants against Feline Calicivirus
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Kim Kyoung-Lan
Kim Young-Mog
Lee Eun-Woo
Lee Dae-Sung
Lee Myung-Suk
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Abstract
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In an effort to discover an antiviral substance against noroviruse (NV), which causes gastroenteritis illness world-wide, several plants including spices and herbs were evaluated for their antiviral activities against feline calicivirus (FCV) as a surrogate for NV. Among them, methanolic extract of green tea (Camellia sinensis L.) exhibited significant antiviral activity against FCV. After treatment with green tea extract (3.13 ㎎/㎖) for 1 hr, FCV was completely inactivated. The antiviral activity of green tea extract against FCV was also determined to be doseand time- dependent. The results obtained in this study suggested that green tea will be effective in the prevention of food-borne diseases caused by NV.
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KEYWORD
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Norovirus, feline calicivirus, food-borne pathogens, antiviral activity
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